As I said in this post (https://blog.medium.com/nominating-pubs-bb4923442864): "This focus on topically-focused publications doesn’t mean we won’t add more general interest publications to the program in the future. Right now, however, we’re focused on working with editors running publications that speak to very specific audiences"
While the end goal is allowing most publications into the program, publications with a high amount stories that don't fit with our quality guidelines wouldn't ever be a good fit for the program. This could include meta, erotica, crypto air drops, etc. More about that: https://help.medium.com/hc/en-us/articles/360006362473-Medium-s-Quality-Guidelines-How-real-humans-review-stories-for-Boost